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Unlike cisplatin and similarly to other antiarthritic gold drugs, auranofin appears to exert its activity through inhibition of enzyme activities rather than DNA damage

Evidence level: Unsupported by the cited record Sources: Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice., Nicotinamide N-methyltransferase inhibition mitigates obesity-related metabolic dysfunction., ClinicalTrials.gov exact-name search, accessed 2026-07-12 How to read this: Direct efficacy findings come from obese mice, not human trials

A., Carroll, V

New York: McGraw-Hill, 2006 Kliegman RM, Behrman RE, Jenson HB, et al

Leszczyniecka M, Roberts T, Dent P, Grant S, Fisher PB